Protean City (and indeed most of the known multiverse) includes people with incredible abilities and powers created by genetic abnormalities. Although there is talk of a single mutant gene, this has not been backed up by modern study.
“"Windshear, full of Hot Air and out of time." Windshear is a long-term staple of Protean City's...Windshear
“Hermosa Vida is a defender of the B.A.S.H. and mutant superhero of the early Modern Generation...Hermosa Vida